Monday Seminar // Browsing posts in Monday Seminar
Towards ubiquitous and continuous measurement of the brain function with fNIRS – 2/5/2018
Hasan Ayaz Drexel University Abstract: Significant progress has been made over the last decades in understanding the physiological and neural bases of cognitive processes and behavior. The advent of new and improved brain imaging tools, that allow monitoring brain activity in natural environments, is expected to provide a complementary perspective into the relationship of […]
Oxytocin: A New Approach to Treating Addiction – 1/29/2018
Mary Lee National Institutes of Health Abstract: Direct evidence of cerebrospinal fluid penetrance of oxytocin after intranasal and intravenous administration and effect of systemic oxytocin administration on methylphenidate-induced changes in accumbal dopamine levels and methylphenidate self-administration Background: Diffusion of peptides such as Oxytocin (OT), when delivered intravenously (IV), across the blood brain barrier is restricted. […]
How the brain controls behavior: Using flies to study motor control at the circuit level – 9/25/2017
Claire McKellar Janelia Research Campus/HHMI Abstract: Investigating how the nervous system controls complex behaviors in simple animals could reveal mechanisms that are fundamental to behavior across species. Cutting-edge genetic tools in flies allow control over multiple neuron types, giving access to a circuit-level view of behavioral control. I am addressing two important questions about behavioral […]
Seeing What Others Cannot See – 10/2/2017
Thomas G. West Author of Thinking Like Einstein and In the Mind’s Eye Krasnow Institute Advisory Board Member Abstract: For over 25 years, Thomas West has been a leading advocate for the importance of visual thinking, visual technologies and the creative potential of individuals with dyslexia and other learning differences. In this new book, Seeing […]
Modeling and quantification of astrocyte activity from calcium imaging data – 10/16/2017
Guoqiang Yu Virginia Polytechnic Institute and State University Abstract: Recent studies have suggested that astrocytes exert proactive regulatory effects on brain information processing and that they are deeply involved in normal brain development and disease pathology. Recording astrocyte activity is now technically feasible, due to recent advances in modern microscopy and ultrasensitive cell-type specific genetically […]
Cellular and molecular aberrations in Neurodevelopmental disorders associated with autism, intellectual disability and related disorders – 10/30/2017
Jyothi Arikkath University of Nebraska Medical Center Abstract: Autism spectrum disorders represent a heterogeneous group of neurodevelopmental disorders characterized by deficits in social interaction, communication skills and repetitive behavior. These disorders are often co-morbid with other disorders including intellectual disability. A major challenge in autism and related disorders has been to define cellular and molecular […]
The Future for Advanced Studies: Integrating Team Science and Convergence – 11/6/2017
Jim Olds Schar School and Krasnow Institute George Mason University Abstract: When we think of ‘Advanced Studies’ in the context of science, the Institute for Advanced Studies at Princeton (IAS) comes to mind as well as the notion of science at the ‘sticky edges’ of the disciplines unbundled from the teaching aspects of the academy. […]
The Challenge of Modeling Cognition for Computational Social Science – 3/20/2017
Bill Kennedy Assistant Professor Center for Social Complexity Computational Social Science Program Abstract: Computational Social Science (CSS) uses models of cognition, mostly human cognition. Zero intelligence agents may be useful for some economic experiments and agents with preferences about their neighbors and moving randomly may demonstrate the emergence of segregation, but better models of individual’s […]
A novel role for Drosophila Amyloid Precursor Protein in regulating axonal retrograde trafficking of selective cargoes – 3/6/2017
Tanja Godenschwege Florida Atlantic University Department of Biological Sciences Abstract: One of the pathological hallmarks of Alzheimer’s Disease (AD) is the presence of β-amyloid plaques that result from abnormal processing of the Amyloid Precursor Protein (APP). Although a great deal is known about AD pathology, relatively little is known about the normal biological function of […]
Of Form and Function: Stochastic Optimization Elucidates Role of Dynamics in Proteinopathies – 2/27/2017
Amarda Shehu Associate Professor, Department of Computer Science George Mason University Abstract: All processes that maintain and replicate a living cell involve moving biomolecules. The energy landscape underscores the inherent nature of biomolecules as dynamic systems interconverting between structures with varying energies. Biomolecular structural transitions regulate diverse processes, such as allosteric signaling and catalysis, and […]
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