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Monday Seminar, Upcoming Monday Seminars | Comments Off on Association of a functional polymorphism of the human CHRFAM7A gene with inflammatory response mediators after spinal cord injury – 1/23/2017

Association of a functional polymorphism of the human CHRFAM7A gene with inflammatory response mediators after spinal cord injury – 1/23/2017

Robert Lipsky, Ph.D. Director, Translational Research Inova Neurosciences Institute Inova Health System Abstract: A complex system of activated immune cells and cytokines contributes to the inflammatory response after spinal cord injury (SCI).  Specific receptors are the targets of cytokines in these cells. It is known that the alpha 7 nicotinic acetylcholine receptor, α7nAChR, plays a […]

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Monday Seminar, Upcoming Monday Seminars | Comments Off on Of Form and Function: Stochastic Optimization Eludicates Role of Dynamics in Proteinopathies – 2/20/2017

Of Form and Function: Stochastic Optimization Eludicates Role of Dynamics in Proteinopathies – 2/20/2017

Amarda Shehu Associate Professor, Department of Computer Science George Mason University Abstract: All processes that maintain and replicate a living cell involve moving biomolecules. The energy landscape underscores the inherent nature of biomolecules as dynamic systems interconverting between structures with varying energies. Biomolecular structural transitions regulate diverse processes, such as allosteric signaling and catalysis, and […]

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Monday Seminar, Upcoming Monday Seminars | Comments Off on Circuit analysis of posterior parietal function – 11/21/2016

Circuit analysis of posterior parietal function – 11/21/2016

Professor Rebecca Burwell Department of Cognitive, Linguistic and Psychological Sciences Brown University Abstract: Parahippocampal connections with posterior parietal cortex and the thalamus are well documented for the rodent and primate brains, but there are many open questions about the functions of these circuits. In the rodent brain, the postrhinal cortex, posterior parietal cortex , and […]

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Monday Seminar, Upcoming Monday Seminars | Comments Off on Predicting How Genetic Mutations Can Cause Disease: Cardiac Arrhythmia as an Example – 12/5/2016

Predicting How Genetic Mutations Can Cause Disease: Cardiac Arrhythmia as an Example – 12/5/2016

Saleet Jafri Krasnow Institute George Mason University Abstract: Understanding how genetic variation manifests itself as phenotype is major unanswered question in biology.  We explore this issue in the context of heart disease.  A certain class of cardiac arrhythmia results from defects in intracellular calcium dynamics.  Of these many can be attributed to genetic mutations in […]

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