Publications

Dumas, T.C. & Foster, T.C. (1995) Developmental increase in CA3-CA1 presynaptic function in the hippocampal slice. Journal of Neurophysiology, 73:1821-1828.

Dumas, T.C. & Foster, T.C. (1997) Development of metabotropic glutamate receptor-mediated synaptic inhibition. NeuroReport, 8:2919-2924.

Dumas, T.C. & Foster, T.C. (1998) Late developmental changes in the ability of adenosine A1 receptors to regulate synaptic transmission in the hippocampus. Developmental Brain Research, 105:137-139.

Dumas, T.C. & Foster, T.C. (1998) Developmental changes in the ability of GABAb receptors to regulate synaptic transmission in the hippocampus. Neuroscience Letters, 248:138-140.

Dumas, T.C., McLaughlin, J.R., Ho, D.Y., Meier, T.J. & Sapolsky, R.M. (1999) Delivery of herpes simplex virus amplicon-based vectors to the dentate gyrus does not alter hippocampal synaptic transmission in vivo. Gene Therapy, 6:1679-1684.

Dumas, T.C., McLaughlin, J.R., Ho, D.Y., Lawrence, M.S. & Sapolsky, R.M. (2000) Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission. Experimental Neurology, 166:180-189.

McLaughlin, J.R., Roozendaal, B., Dumas, T.C., Gupta, A., Ajilore, O., Hsieh, J., Ho, D.Y., Lawrence, M.S., McGaugh, J.L. & Sapolsky, R.M. (2000) Sparing neuronal function post-seizure with gene therapy. Proceedings of the National Academy of Sciences (USA), 97:12804-12809.

Yenari, M.A., Dumas, T.C., Sapolsky, R.M. & Steinberg, G.K., (2000) Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors. In Slikker W & Trembly B (Eds), Neuroprotective Agents: 5th International Conference, Annals of the New York Acadamy of Sciences, 939:340-357.

Yenari, M.A., Dumas, T.C., Sapolsky, R.M. & Steinberg, G.K., (2000) Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors. Neurology Research, 23:543-552.

Foster, T.C. & Dumas, T.C. (2001) Mechanisms for increased hippocampal CA3-CA1 synaptic strength following differential experience. Journal of Neurophysiology, 85:1377-1383.

Dumas, T.C. & Sapolsky, R.M. (2001) Gene therapy against neurological insults: sparing neurons versus sparing function. Trends in Neuroscience, 24:695-700.

Lee, A.L., Dumas, T.C., Tarapore, P.E., Webster, B.R., Ho, D.Y., Kaufer, D. & Sapolsky, R.M. (2003) Potassium channel gene therapy can prevent neuron death resulting from necrotic insults. Journal of Neurochemistry, 86:1079-88.

Dumas, T.C. (2004) Early eyelid opening enhances spontaneous alternation and accelerates the development of perforant path synaptic strength in the hippocampus of juvenile rats. Developmental Psychobiology, 45:1-9.

Dumas, T.C., Powers, E.C., Tarapore, P.E. & Sapolsky, R.M. (2004) Overexpression of calbindin D28k in dentate granule cells potentiates mossy fiber presynaptic function, reduces long-term potentiation and impairs hippocampal-dependent memory. Hippocampus, 14:701-709.

Kaufer, D., Ogle, W.O., Pincus, Z.S., Clark, K., Nicholas A.C., Dinkel, K.M., Dumas, T.C., Ferguson, D., Lee, A.L., Winters, M. & Sapolsky, R.M. (2004) Restructuring the neuronal stress response with anti-glucocorticoid gene delivery. Nature Neuroscience, 7:947-953.

Nair, S., Karst, H., Dumas, T., Phillips, R., Sapolsky, R., Rumpff-van Essen, L., Maslam, S., Lucassen, P., & Joels, M. (2004) Gene expression profiles associated with survival of individual rat dentate cells after endogenous corticosteroid deprivation. European Journal of Neuroscience, 20:3233-3243.

Dumas, T.C. (2005a) Late postnatal maturation of excitatory synaptic transmission permits the expression of adult-like hippocampal-dependent behaviors. Hippocampus, 15:562-578.

Xie, X., Dumas, T., Tang, L., Brennan, T., Reeder, T., Winston, T., Klein, R.D., Flores, J., O'Hara, B.F., Heller, H.C., & Franken, P. (2005) Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice. Brain Research, 1052:212-221.

Dumas, T.C. (2005b) Developmental regulation of cognitive abilities: Modified composition of a molecular switch turns on associative learning. Progress in Neurobiology, 76:189-211.

Chapters:

Yenari, M.A., Dumas, T.C., Sapolsky, R.M. & Steinberg, G.K., (2000) The role of gene therapy in acute cerebral ischemia. In J. Krieglstein & S. Klumpp (Eds), Pharmacology of Cerebral Ischemia, Medpharm Scientific Publishers, Stuttgart, p. 457-472.

Dumas, T.C. & Rudy, J.W. Development of the Hippocampal Memory System: Creating Networks and Modifiable Synapses. In Handbook of developmental and Comparative Neuroscience: Epigenetics, Evolution, & Behavior. Oxford University Press. Invited chapter. In Press.