An intense review of neurobiology for graduate students interested in studying how nerve cells integrate and transmit signals, and how behavior emerges from the integrated actions of populations or circuits of nerve cells. The course covers electrical and biochemical properties of single neurons, and electrical and chemical communication between neurons. Emphasis is on mathematical descriptions and computational techniques used to study and understand neurons and networks of neurons.Learn how to ask and answer questions about neurobiology using computational techniques

GRADING
Homework
            Assigned almost every week.
            Due the following class period
            10% of grade
            Homework turned in one week late will be graded, but marked down one letter grade
            Homework not accepted more than one week late

Exams
            Midterm counts 45% of grade
            Final counts 45% of grade, is NOT cummulative
            No re-tests

WEEK/DATE	TOPIC	READING
1 1/25	Introduction, Electrical Circuit Theory, Equilibrium Lecture in ppt	J&W appendix , Chap 2,3
2 2/1	Computer Lab - ionic concentrations (12 - 1:20) Cable theory (1:30-2:45) lecture in ppt	J&W 4, Rall chapter
3 2/8	Neurons as conductors of electricity
4 2/15	Computer Lab - Cable (12-1:20) Review Cable theory(1:30-2:45)	BoG Chap 5
5 2/22	Ionic Basis of Action Potential Lecture	J&W Chap 5,6
6 3/1	Computer Labs - Squid (12-1:20) Membrane Channels(1:30-2:45)	BoG Chap 4 J&W Chap 7
7 3/08	Computer Labs - burster (12-1:20) Review (1:30-2:50)
8 3/22	MIDTERM (Lectures 1-6)
9 3/29	Single channel Analysis	J&W Chap 8,9,10
10 4/5	Single Channel Analysis lecture in ppt	J&W Chap 8,9,10
11 4/2	Pre-synaptic transmission lecture in ppt	J&W Chap 11
12 4/19	Post-synaptic transmission, GAP junctions lecture in ppt	J&W Chap 12, 13
13 4/26	Synaptic plasticity Lecture in ppt	J&W Chap 15
15 5/3	Review
5/10	FINAL, 12 Noon - 2:50 PM (Lectures 8-14)